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USC-OGP 2-DE database
Two-dimensional polyacrylamide gel electrophoresis database
USC-OGP 2-DE database
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Searching in 'USC-OGP 2-DE database' for entry
matching:
IPYR_HUMAN
USC-OGP 2-DE database
:
IPYR_HUMAN
IPYR_HUMAN
General information about the entry
View entry in simple text format
Entry name
IPYR_HUMAN
Primary accession number
Q15181
integrated into USC-OGP 2-DE database on
January 17, 2017 (release 1)
2D Annotations were last modified on
January 17, 2017 (version 1)
General Annotations were last modified on
April 5, 2017 (version 2)
Name and origin of the protein
Description
RecName: Full=Inorganic pyrophosphatase; EC=3.6.1.1; AltName: Full=Pyrophosphate phospho-hydrolase; Short=PPase;.
Gene name
Name=PPA1
Synonyms=IOPPP, PP
Annotated species
Homo sapiens (Human) [TaxID:
9606
]
Taxonomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]
2D GEL CHARACTERIZATION
Author 1., Author 2.
Submitted (Mar-2011) to Current
2D PAGE maps for identified proteins
How to interpret a protein
UVEAL_MELANOMA_3-10
{UVEAL MELANOMA 3-10}
Homo sapiens (Human)
map experimental info
UVEAL_MELANOMA_3-10
MAP LOCATIONS:
SPOT OGP-1233
:
pI=5.54; Mw=33419
Cross-references
UniProtKB/Swiss-Prot
Q15181; IPYR_HUMAN.
2D PAGE maps for identified proteins
How to interpret a protein map
You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
Warning 1
: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
Warning 2
: the 2D PAGE map is built on demand. This may take some few seconds to be computed.
External data extracted from
UniProtKB/Swiss-Prot
Extracted from
UniProtKB/Swiss-Prot
, release:
0.0
Entry name
IPYR_HUMAN
Primary accession number
Q15181
Secondary accession number(s)
Q2M348 Q5SQT7 Q6P7P4 Q9UQJ5 Q9Y5B1
Sequence was last modified on
May 30, 2000 (version 2)
Annotations were last modified on
March 15, 2017 (version 168)
Name and origin of the protein
Description
RecName: Full=Inorganic pyrophosphatase; EC=3.6.1.1; AltName: Full=Pyrophosphate phospho-hydrolase; Short=PPase;
Gene name
Name=PPA1
Synonyms=IOPPP, PP
Encoded on
Name=PPA1; Synonyms=IOPPP, PP
Keywords
Acetylation
;
Complete proteome
;
Cytoplasm
;
Direct protein sequencing
;
Hydrolase
;
Magnesium
;
Metal-binding
;
Phosphoprotein
;
Polymorphism
;
Reference proteome
.
Copyright
Copyrighted by the UniProt Consortium, see
http://www.uniprot.org/help/license
. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL
AF154065; AAD34643.1
; -; mRNA
EMBL
AB026723; BAA84702.1
; -; mRNA
EMBL
AF217186; AAG36780.1
; -; mRNA
EMBL
AF092439; AAP97214.1
; -; mRNA
EMBL
AF119665; AAF17222.1
; -; mRNA
EMBL
AL731540; CAI13692.1
; -; Genomic_DNA
EMBL
BC001022; AAH01022.3
; -; mRNA
EMBL
BC061581; AAH61581.2
; -; mRNA
EMBL
BC105034; AAI05035.1
; -; mRNA
EMBL
BC105036; AAI05037.1
; -; mRNA
EMBL
BC107882; AAI07883.1
; -; mRNA
EMBL
AF108211; AAD24964.1
; -; mRNA
EMBL
Z48605; CAA88494.1
; -; mRNA
CCDS
CCDS7299.1; -
; .
RefSeq
NP_066952.1; NM_021129.3
; .
UniGene
Hs.437403; -
; .
ProteinModelPortal
Q15181; -
; .
SMR
Q15181; -
; .
BioGrid
111460; 31
; .
IntAct
Q15181; 12
; .
MINT
MINT-3030968; -
; .
STRING
9606.ENSP00000362329; -
; .
iPTMnet
Q15181; -
; .
PhosphoSitePlus
Q15181; -
; .
BioMuta
PPA1; -
; .
DMDM
8247940; -
; .
REPRODUCTION-2DPAGE
IPI00015018; -
; .
EPD
Q15181; -
; .
PaxDb
Q15181; -
; .
PeptideAtlas
Q15181; -
; .
PRIDE
Q15181; -
; .
TopDownProteomics
Q15181; -
; .
DNASU
5464; -
; .
Ensembl
ENST00000373232; ENSP00000362329
; ENSG00000180817; .
GeneID
5464; -
; .
KEGG
hsa:5464; -
; .
CTD
5464; -
; .
DisGeNET
5464; -
; .
GeneCards
PPA1; -
; .
H-InvDB
HIX0032502; -
; .
HGNC
HGNC:9226; PPA1
; .
HPA
HPA019878; -
; .
HPA
HPA020096; -
; .
MIM
179030; gene
; .
neXtProt
NX_Q15181; -
; .
OpenTargets
ENSG00000180817; -
; .
PharmGKB
PA33550; -
; .
eggNOG
KOG1626; Eukaryota
; .
eggNOG
COG0221; LUCA
; .
GeneTree
ENSGT00390000017004; -
; .
HOGENOM
HOG000195569; -
; .
HOVERGEN
HBG000491; -
; .
InParanoid
Q15181; -
; .
KO
K01507; -
; .
OMA
GHKDENT; -
; .
OrthoDB
EOG091G0KFV; -
; .
PhylomeDB
Q15181; -
; .
TreeFam
TF300887; -
; .
BRENDA
3.6.1.1; 2681
; .
Reactome
R-HSA-379716; Cytosolic tRNA aminoacylation
; .
Reactome
R-HSA-71737; Pyrophosphate hydrolysis
; .
ChiTaRS
PPA1; human
; .
GenomeRNAi
5464; -
; .
PRO
PR:Q15181; -
; .
Proteomes
UP000005640; Chromosome 10
; .
Bgee
ENSG00000180817; -
; .
CleanEx
HS_PPA1; -
; .
ExpressionAtlas
Q15181; baseline and differential
; .
Genevisible
Q15181; HS
; .
GO
GO:0005737; C:cytoplasm
; TAS:UniProtKB; .
GO
GO:0005829; C:cytosol
; TAS:Reactome; .
GO
GO:0070062; C:extracellular exosome
; IDA:UniProtKB; .
GO
GO:0004427; F:inorganic diphosphatase activity
; EXP:Reactome; .
GO
GO:0000287; F:magnesium ion binding
; IEA:InterPro; .
GO
GO:0071344; P:diphosphate metabolic process
; TAS:Reactome; .
GO
GO:0006796; P:phosphate-containing compound metabolic process
; TAS:ProtInc; .
GO
GO:0006418; P:tRNA aminoacylation for protein translation
; TAS:Reactome; .
CDD
cd00412; pyrophosphatase
; 1; .
Gene3D
3.90.80.10; -
; 1; .
InterPro
IPR008162; Pyrophosphatase
; .
PANTHER
PTHR10286; PTHR10286
; 1; .
Pfam
PF00719; Pyrophosphatase
; 1; .
SUPFAM
SSF50324; SSF50324
; 1; .
PROSITE
PS00387; PPASE
; 1; .
Gateways to other related servers
The World-2DPAGE Constellation
- Entry point to the world-wide 2-DPAGE resources.
World-2DPAGE Repository
- A public repository for gel-based proteomics data linked to protein identification published in the literature.
World-2DPAGE Portal
- A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
SWISS-2DPAGE
- The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
ExPASy
- The resources web server of the
Swiss Institute of Bioinformatics
Database constructed and maintained by
Angel Garcia
, using the
Make2D-DB II
package (
ver. 3.10.2
) from the
World-2DPAGE Constellation
of the
ExPASy web server
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